Call us to set up an appointment! 403-793-8484

Brooks Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it attempts to restore itself to normal before the harm was achieved. Soft Health and Healing Clinic is always amazed at what the body can do! Soft Health and Healing Clinic sees its Brooks chiropractic care as a partner of the body’s system in healing especially when there is spine pain. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is showing value in its ability to interrupt the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to its cellular level via autophagy, the natural process during which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin increased autophagy and lessened the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin prevents intervertebral disc degeneration by promoting autophagy. (3) Wow. Soft Health and Healing Clinic is encouraged by this research to see just how well melatonin can perform for Brooks back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is a very common malady seen at Soft Health and Healing Clinic that positive news of melatonin’s benefits are quite rousing. A recent study described that melatonin could modify the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin decreased the inflammatory cell collection and reduced the release of linked inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin interrupted the IL-1B feedback loop, researchers proposed that melatonin may provide the healing process of intervertebral discs after damage has already been done. (1) Soft Health and Healing Clinic continues following the new research on the role inflammation plays in Brooks disc degeneration and melatonin’s role in tackling it.

INFLAMMATION AND MELATONIN

The significance of melatonin in helping to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other mechanisms is quite fitting. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by hindering the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) activities. (1) Melatonin’s specific influence on inflammation and disc degeneration is most interesting to Soft Health and Healing Clinic and our Brooks back pain patients.

CONTACT Soft Health and Healing Clinic

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management handles disc degeneration for relief of chronic low back pain in her patient.

Schedule your Brooks chiropractic appointment with Soft Health and Healing Clinic now. We can talk about the role inflammation plays in your back pain experience and how melatonin may help with the related disc degeneration.

 
Soft Health and Healing Clinic shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
« View All Nutrition Articles
"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."